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Torque modulates nucleosome stability and facilitates H2A/H2B dimer loss

The nucleosome, the fundamental packing unit of chromatin, has a distinct chirality: 147 bp of DNA are wrapped around the core histones in a left-handed, negative superhelix. It has been suggested that this chirality has functional significance, particularly in the context of the cellular processes...

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Detalles Bibliográficos
Autores principales: Sheinin, Maxim Y., Li, Ming, Soltani, Mohammad, Luger, Karolin, Wang, Michelle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848035/
https://www.ncbi.nlm.nih.gov/pubmed/24113677
http://dx.doi.org/10.1038/ncomms3579