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Torque modulates nucleosome stability and facilitates H2A/H2B dimer loss
The nucleosome, the fundamental packing unit of chromatin, has a distinct chirality: 147 bp of DNA are wrapped around the core histones in a left-handed, negative superhelix. It has been suggested that this chirality has functional significance, particularly in the context of the cellular processes...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848035/ https://www.ncbi.nlm.nih.gov/pubmed/24113677 http://dx.doi.org/10.1038/ncomms3579 |