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Cooccurrence of Mycotoxins in Maize and Poultry Feeds from Brazil by Liquid Chromatography/Tandem Mass Spectrometry

The objective of this study was to quantitatively evaluate mycotoxins in samples of maize and poultry feed produced in Brazil. A multimycotoxin method based on HPLC-MS/MS was applied to investigate the occurrence of toxical fungal metabolites in 119 samples collected from poultry feed factory integr...

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Autores principales: de Souza, Maria de Lourdes Mendes, Sulyok, Michael, Freitas-Silva, Otniel, Costa, Sônia Soares, Brabet, Catherine, Machinski Junior, Miguel, Sekiyama, Beatriz Leiko, Vargas, Eugenia Azevedo, Krska, Rudolf, Schuhmacher, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848270/
https://www.ncbi.nlm.nih.gov/pubmed/24348157
http://dx.doi.org/10.1155/2013/427369
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author de Souza, Maria de Lourdes Mendes
Sulyok, Michael
Freitas-Silva, Otniel
Costa, Sônia Soares
Brabet, Catherine
Machinski Junior, Miguel
Sekiyama, Beatriz Leiko
Vargas, Eugenia Azevedo
Krska, Rudolf
Schuhmacher, Rainer
author_facet de Souza, Maria de Lourdes Mendes
Sulyok, Michael
Freitas-Silva, Otniel
Costa, Sônia Soares
Brabet, Catherine
Machinski Junior, Miguel
Sekiyama, Beatriz Leiko
Vargas, Eugenia Azevedo
Krska, Rudolf
Schuhmacher, Rainer
author_sort de Souza, Maria de Lourdes Mendes
collection PubMed
description The objective of this study was to quantitatively evaluate mycotoxins in samples of maize and poultry feed produced in Brazil. A multimycotoxin method based on HPLC-MS/MS was applied to investigate the occurrence of toxical fungal metabolites in 119 samples collected from poultry feed factory integrated poultry farms: maize grain (74), poultry feed (36), and feed factory residue (9). Twenty of 101 fungal metabolites investigated were detected and quantified in the samples: aflatoxins B(1), B(2), G(1), and G(2), fumonisins B(1), B(2), and B(3), hydrolyzed fumonisin B(1), zearalenone, agroclavine, chanoclavine, deoxynivalenol, and nivalenol, and enniatin A, A(1), B, B(1), beauvericin, kojic acid, and moniliformin. Most samples were contaminated with more than one mycotoxin. All samples were contaminated with fumonisins, with medians values of 1,840 μg/kg, 239 μg/kg, and 23,676 μg/kg for maize, feed, and factory residue samples, respectively. Surprisingly, beauvericin was detected in more than 90% of samples. The median contaminations of aflatoxin and trichothecenes were low, near LOD values. The factory residue presented highest contamination levels for all mycotoxins. This is the first study dealing with agroclavine, chanoclavine, enniatin A, A(1), B, B(1), beauvericin, and kojic acid contamination of maize and poultry feeds from Brazil.
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spelling pubmed-38482702013-12-12 Cooccurrence of Mycotoxins in Maize and Poultry Feeds from Brazil by Liquid Chromatography/Tandem Mass Spectrometry de Souza, Maria de Lourdes Mendes Sulyok, Michael Freitas-Silva, Otniel Costa, Sônia Soares Brabet, Catherine Machinski Junior, Miguel Sekiyama, Beatriz Leiko Vargas, Eugenia Azevedo Krska, Rudolf Schuhmacher, Rainer ScientificWorldJournal Research Article The objective of this study was to quantitatively evaluate mycotoxins in samples of maize and poultry feed produced in Brazil. A multimycotoxin method based on HPLC-MS/MS was applied to investigate the occurrence of toxical fungal metabolites in 119 samples collected from poultry feed factory integrated poultry farms: maize grain (74), poultry feed (36), and feed factory residue (9). Twenty of 101 fungal metabolites investigated were detected and quantified in the samples: aflatoxins B(1), B(2), G(1), and G(2), fumonisins B(1), B(2), and B(3), hydrolyzed fumonisin B(1), zearalenone, agroclavine, chanoclavine, deoxynivalenol, and nivalenol, and enniatin A, A(1), B, B(1), beauvericin, kojic acid, and moniliformin. Most samples were contaminated with more than one mycotoxin. All samples were contaminated with fumonisins, with medians values of 1,840 μg/kg, 239 μg/kg, and 23,676 μg/kg for maize, feed, and factory residue samples, respectively. Surprisingly, beauvericin was detected in more than 90% of samples. The median contaminations of aflatoxin and trichothecenes were low, near LOD values. The factory residue presented highest contamination levels for all mycotoxins. This is the first study dealing with agroclavine, chanoclavine, enniatin A, A(1), B, B(1), beauvericin, and kojic acid contamination of maize and poultry feeds from Brazil. Hindawi Publishing Corporation 2013-11-14 /pmc/articles/PMC3848270/ /pubmed/24348157 http://dx.doi.org/10.1155/2013/427369 Text en Copyright © 2013 Maria de Lourdes Mendes de Souza et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
de Souza, Maria de Lourdes Mendes
Sulyok, Michael
Freitas-Silva, Otniel
Costa, Sônia Soares
Brabet, Catherine
Machinski Junior, Miguel
Sekiyama, Beatriz Leiko
Vargas, Eugenia Azevedo
Krska, Rudolf
Schuhmacher, Rainer
Cooccurrence of Mycotoxins in Maize and Poultry Feeds from Brazil by Liquid Chromatography/Tandem Mass Spectrometry
title Cooccurrence of Mycotoxins in Maize and Poultry Feeds from Brazil by Liquid Chromatography/Tandem Mass Spectrometry
title_full Cooccurrence of Mycotoxins in Maize and Poultry Feeds from Brazil by Liquid Chromatography/Tandem Mass Spectrometry
title_fullStr Cooccurrence of Mycotoxins in Maize and Poultry Feeds from Brazil by Liquid Chromatography/Tandem Mass Spectrometry
title_full_unstemmed Cooccurrence of Mycotoxins in Maize and Poultry Feeds from Brazil by Liquid Chromatography/Tandem Mass Spectrometry
title_short Cooccurrence of Mycotoxins in Maize and Poultry Feeds from Brazil by Liquid Chromatography/Tandem Mass Spectrometry
title_sort cooccurrence of mycotoxins in maize and poultry feeds from brazil by liquid chromatography/tandem mass spectrometry
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848270/
https://www.ncbi.nlm.nih.gov/pubmed/24348157
http://dx.doi.org/10.1155/2013/427369
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