Cargando…

LEDGINs, a novel class of antivirals targeting HIV integrase during integration and assembly

Detalles Bibliográficos
Autor principal:	Debyser, Zeger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Oral Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848282/ http://dx.doi.org/10.1186/1742-4690-10-S1-O44

Ejemplares similares

LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions
por: Desimmie, Belete Ayele, et al.
Publicado: (2013)

LEDGIN-mediated Inhibition of Integrase–LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV
por: Vranckx, Lenard S., et al.
Publicado: (2016)

Correction to: LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions
por: Desimmie, Belete Ayele, et al.
Publicado: (2020)

Impact of LEDGIN treatment during virus production on residual HIV-1 transcription
por: Vansant, Gerlinde, et al.
Publicado: (2019)

LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs
por: Schrijvers, Rik, et al.
Publicado: (2012)

Correction: LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs
por: Schrijvers, Rik, et al.
Publicado: (2020)

HIV-1 integrase SUMOylation and viral replication
por: Zamborlini, Alessia, et al.
Publicado: (2011)

LEDGF/p75 controls 3D-localization of HIV-1 provirus in the nuclear compartment of infected cells
por: Boll, Annegret, et al.
Publicado: (2013)

Bromodomain and extra-terminal (BET) proteins target Moloney murine leukemia virus integration to transcription start sites
por: De Riick, Jan, et al.
Publicado: (2013)

2-Hydroxyisoquinoline-1,3(2H, 4H)diones (HQDs), novel inhibitors of the HIV integrase catalytic activity with a high barrier to resistance
por: Christ, Frauke, et al.
Publicado: (2013)

Investigation of anti-HIV activity, cytotoxicity and HIV integrase inhibitory activity of polyherbal formulation BH extracts
por: Balraj, S, et al.
Publicado: (2014)

Cellular Cofactors of Lentiviral Integrase: From Target Validation to Drug Discovery
por: Taltynov, Oliver, et al.
Publicado: (2012)

HIV Virions as Nanoscopic Test Tubes for Probing Oligomerization of the Integrase Enzyme
por: Borrenberghs, Doortje, et al.
Publicado: (2014)

Dynamic Oligomerization of Integrase Orchestrates HIV Nuclear Entry
por: Borrenberghs, Doortje, et al.
Publicado: (2016)

A Symmetric Region of the HIV-1 Integrase Dimerization Interface Is Essential for Viral Replication
por: Serrao, Erik, et al.
Publicado: (2012)

Will LEDGIN molecules be able to play a role in a cure for HIV infection?
por: Mesplède, Thibault, et al.
Publicado: (2016)

Persistent production of an integrase-deleted HIV-1 variant with no resistance mutation and wild-type proviral DNA in a treated patient
por: Trabaud, MA, et al.
Publicado: (2014)

Inhibitors of the integrase–transportin-SR2 interaction block HIV nuclear import
por: Demeulemeester, Jonas, et al.
Publicado: (2018)

Activity of the integrase inhibitor S/GSK1349572 in subjects with HIV exhibiting raltegravir resistance: week 24 results of the VIKING study (ING112961)
por: Eron, J, et al.
Publicado: (2010)

Studies on HIV integrase-LEDGF/p75 interaction inhibitory activity of isatine derivative using the alpha screen luminescent proximity assay
por: Selvam, Periyasamy
Publicado: (2012)

HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors
por: Koneru, Pratibha C, et al.
Publicado: (2019)

LEDGF/p75 is critical but not essential for multiple-round HIV 1 replication
por: Schrijvers, RLG, et al.
Publicado: (2010)

Post-mitotic BET-induced reshaping of integrase quaternary structure supports wild-type MLV integration
por: Borrenberghs, Doortje, et al.
Publicado: (2019)

Coordinated changes of HIV-1 Gag and Env during assembly and maturation
por: Kräusslich, Hans-Georg
Publicado: (2013)

HIV-1 acetylated integrase is targeted by KAP1 (TRIM28) to inhibit viral integration
por: Allouch, Awatef, et al.
Publicado: (2009)

Optimization and antiviral analysis of peptide ligands for the HIV-1 packaging signal PSI
por: Dietz, Julia, et al.
Publicado: (2006)

Antimalarial chloroquine metamorphosed into antiviral agent against HIV with four modes of actions
por: Chandramohan, M, et al.
Publicado: (2012)

O017: A novel antiviral technology for air filtration
por: Pelet, T, et al.
Publicado: (2013)

Development of Bevirimat (PA-457): first-in-class HIV maturation inhibitor
por: Allaway, Graham P
Publicado: (2006)

Novel pathways of transcriptional and post-transcriptional regulation of post-integrative HIV-1 latency
por: Marcello, A, et al.
Publicado: (2010)

Integrase and integration: biochemical activities of HIV-1 integrase
por: Delelis, Olivier, et al.
Publicado: (2008)

Structural basis for germline gene usage of a potent class of antibodies targeting the CD4 binding site of HIV-1 gp120
por: West, AP, et al.
Publicado: (2012)

GCN5-dependent acetylation of HIV-1 integrase enhances viral integration
por: Terreni, Mariaelena, et al.
Publicado: (2009)

Raltegravir: first in class HIV integrase inhibitor
por: Temesgen, Zelalem, et al.
Publicado: (2008)

Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach
por: Sirous, Hajar, et al.
Publicado: (2019)

Novel and unexpected cellular partners for HIV-1 integrase and Tat
por: Giacca, Mauro
Publicado: (2009)

Novel therapeutic strategies targeting HIV integrase
por: Quashie, Peter K, et al.
Publicado: (2012)

Impact of the HIV integrase genetic context on the phenotypic expression and in vivo dynamics of integrase inhibitor resistance mutations
por: Nguyen, Nga, et al.
Publicado: (2013)

Measurements of total and integrated HIV DNA demonstrate sporadic blips of unintegrated HIV DNA in HIV-positive patients on HAART
por: Mexas, A, et al.
Publicado: (2010)

Four days a week and less on appropriate antiviral combinations provided long-term optimal control over HIV-1 in 92 patients
por: Leibowitch, Jacques, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_4gdqmbsecm80rbsqjsbu7a9cnl