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MicroRNA-9 regulates survival of chondroblasts and cartilage integrity by targeting protogenin

BACKGROUND: Studies have shown the roles of miR-9 and its validated target, protogenin (PRTG) in the differentiation of chondroblasts to chondrocyte and in the pathogenesis of osteoarthritis (OA). We hypothesized that miR-9 plays a distinct role in endochondral ossification and OA pathogenesis and t...

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Detalles Bibliográficos
Autores principales: Song, Jinsoo, Kim, Dongkyun, Chun, Churl-Hong, Jin, Eun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848287/
https://www.ncbi.nlm.nih.gov/pubmed/24007463
http://dx.doi.org/10.1186/1478-811X-11-66