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MicroRNA-9 regulates survival of chondroblasts and cartilage integrity by targeting protogenin
BACKGROUND: Studies have shown the roles of miR-9 and its validated target, protogenin (PRTG) in the differentiation of chondroblasts to chondrocyte and in the pathogenesis of osteoarthritis (OA). We hypothesized that miR-9 plays a distinct role in endochondral ossification and OA pathogenesis and t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848287/ https://www.ncbi.nlm.nih.gov/pubmed/24007463 http://dx.doi.org/10.1186/1478-811X-11-66 |