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Carbon Monoxide Attenuates Dextran Sulfate Sodium-Induced Colitis via Inhibition of GSK-3β Signaling

Endogenous carbon monoxide (CO) is produced by heme oxygenase-1 (HO)-1 which mediates the degradation of heme into CO, iron, and biliverdin. Also, CO ameliorates the human inflammatory bowel diseases and ulcerative colitis. However, the mechanism for the effect of CO on the inflammatory bowel diseas...

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Detalles Bibliográficos
Autores principales: Uddin, Md. Jamal, Jeong, Sun-oh, Zheng, Min, Chen, Yingqing, Cho, Gyeong Jae, Chung, Hun Taeg, Joe, Yeonsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848334/
https://www.ncbi.nlm.nih.gov/pubmed/24349609
http://dx.doi.org/10.1155/2013/210563