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Partial loss of Smad signaling during in vitro progression of HPV16-immortalized human keratinocytes

BACKGROUND: Disruption of the transforming growth factor-beta (TGF-β) signaling pathway is observed in many cancers, including cervical cancer, resulting in TGF-β resistance. While normal human keratinocytes (HKc) and human papillomavirus type 16-immortalized HKc (HKc/HPV16) are sensitive to the gro...

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Detalles Bibliográficos
Autores principales:	Altomare, Diego, Velidandla, Rupa, Pirisi, Lucia, Creek, Kim E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848426/ https://www.ncbi.nlm.nih.gov/pubmed/24047375 http://dx.doi.org/10.1186/1471-2407-13-424

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