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Alveolar macrophages of GM-CSF knockout mice exhibit mixed M1 and M2 phenotypes

BACKGROUND: Activin A is a pleiotrophic regulatory cytokine, the ablation of which is neonatal lethal. Healthy human alveolar macrophages (AMs) constitutively express activin A, but AMs of patients with pulmonary alveolar proteinosis (PAP) are deficient in activin A. PAP is an autoimmune lung diseas...

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Detalles Bibliográficos
Autores principales:	Dalrymple, Heidi, Barna, Barbara P, Malur, Anagha, Malur, Achut G, Kavuru, Mani S, Thomassen, Mary Jane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848434/ https://www.ncbi.nlm.nih.gov/pubmed/24044676 http://dx.doi.org/10.1186/1471-2172-14-41

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