Biochemical characterization of protein quality control mechanisms during disease progression in the C22 mouse model of CMT1A

Charcot–Marie–Tooth disease type 1A (CMT1A) is a hereditary demyelinating neuropathy linked with duplication of the peripheral myelin protein 22 (PMP22) gene. Transgenic C22 mice, a model of CMT1A, display many features of the human disease, including slowed nerve conduction velocity and demyelinati...

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Detalles Bibliográficos
Autores principales: Chittoor, Vinita G., Sooyeon, Lee, Rangaraju, Sunitha, Nicks, Jessica R., Schmidt, Jordan T., Madorsky, Irina, Narvaez, Diana C., Notterpek, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848555/
https://www.ncbi.nlm.nih.gov/pubmed/24175617
http://dx.doi.org/10.1042/AN20130024

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