Enhanced levels of double-strand DNA break repair proteins protect ovarian cancer cells against genotoxic stress-induced apoptosis

BACKGROUND: Earlier, proteomic profiling of a Serous Ovarian Carcinoma (SeOvCa) progression model in our lab had identified significantly enriched expression of three double-strand break (DSB) -repair proteins viz. RAD50, NPM1, and XRCC5 in transformed cells over pre-transformed, non-tumorigenic cel...

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Detalles Bibliográficos
Autores principales: Kalra, Rajkumar Singh, Bapat, Sharmila A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848582/
https://www.ncbi.nlm.nih.gov/pubmed/24044516
http://dx.doi.org/10.1186/1757-2215-6-66

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