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A combination of improved differential and global RNA-seq reveals pervasive transcription initiation and events in all stages of the life-cycle of functional RNAs in Propionibacterium acnes, a major contributor to wide-spread human disease
BACKGROUND: Sequencing of the genome of Propionibacterium acnes produced a catalogue of genes many of which enable this organism to colonise skin and survive exposure to the elements. Despite this platform, there was little understanding of the gene regulation that gives rise to an organism that has...
Autores principales: | Lin, Yu-fei, A, David Romero, Guan, Shuang, Mamanova, Lira, McDowall, Kenneth J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848588/ https://www.ncbi.nlm.nih.gov/pubmed/24034785 http://dx.doi.org/10.1186/1471-2164-14-620 |
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