Evaluation of DNA damage in COPD patients and its correlation with polymorphisms in repair genes

BACKGROUND: We investigated a potential link between genetic polymorphisms in genes XRCC1 (Arg399Gln), OGG1 (Ser326Cys), XRCC3 (Thr241Met), and XRCC4 (Ile401Thr) with the level of DNA damage and repair, accessed by comet and micronucleus test, in 51 COPD patients and 51 controls. METHODS: Peripheral...

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Detalles Bibliográficos
Autores principales: da Silva, Andréa Lúcia Gonçalves, da Rosa, Helen Tais, Karnopp, Thaís Evelyn, Charlier, Clara Forrer, Ellwanger, Joel Henrique, Moura, Dinara Jaqueline, Possuelo, Lia Gonçalves, Valim, Andréia Rosane de Moura, Guecheva, Temenouga Nikolova, Henriques, João Antonio Pêgas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848611/
https://www.ncbi.nlm.nih.gov/pubmed/24053728
http://dx.doi.org/10.1186/1471-2350-14-93

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