Cargando…
Integrative genomic and functional profiling of the pancreatic cancer genome
BACKGROUND: Pancreatic cancer is a deadly disease with a five-year survival of less than 5%. A better understanding of the underlying biology may suggest novel therapeutic targets. Recent surveys of the pancreatic cancer genome have uncovered numerous new alterations; yet systematic functional chara...
Autores principales: | Shain, A Hunter, Salari, Keyan, Giacomini, Craig P, Pollack, Jonathan R |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848637/ https://www.ncbi.nlm.nih.gov/pubmed/24041470 http://dx.doi.org/10.1186/1471-2164-14-624 |
Ejemplares similares
-
Breakpoint Analysis of Transcriptional and Genomic Profiles Uncovers Novel Gene Fusions Spanning Multiple Human Cancer Types
por: Giacomini, Craig P., et al.
Publicado: (2013) -
DR-Integrator: a new analytic tool for integrating DNA copy number and gene expression data
por: Salari, Keyan, et al.
Publicado: (2010) -
Genomic Profiling Identifies GATA6 as a Candidate Oncogene Amplified in Pancreatobiliary Cancer
por: Kwei, Kevin A., et al.
Publicado: (2008) -
The Spectrum of SWI/SNF Mutations, Ubiquitous in Human Cancers
por: Shain, A. Hunter, et al.
Publicado: (2013) -
Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer
por: Kim, Young H., et al.
Publicado: (2009)