Deletion of the HAMP domains from the histidine kinase CaNik1p of Candida albicans or treatment with fungicides activates the MAP kinase Hog1p in S. cerevisiae transformants

BACKGROUND: Microorganisms use two-component signal transduction (TCST) systems to regulate the response of the organism to changes of environmental conditions. Such systems are absent from mammalian cells and are thus of interest as drug targets. Fungal TCST systems are usually composed of a hybrid...

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Detalles Bibliográficos
Autores principales: El-Mowafy, Mohammed, Bahgat, Mahmoud M, Bilitewski, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848655/
https://www.ncbi.nlm.nih.gov/pubmed/24044701
http://dx.doi.org/10.1186/1471-2180-13-209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848655/
https://www.ncbi.nlm.nih.gov/pubmed/24044701
http://dx.doi.org/10.1186/1471-2180-13-209

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