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Stem cells isolated from adipose tissue of obese patients show changes in their transcriptomic profile that indicate loss in stemcellness and increased commitment to an adipocyte-like phenotype
BACKGROUND: The adipose tissue is an endocrine regulator and a risk factor for atherosclerosis and cardiovascular disease when by excessive accumulation induces obesity. Although the adipose tissue is also a reservoir for stem cells (ASC) their function and “stemcellness” has been questioned. Our ai...
Autores principales: | Oñate, Blanca, Vilahur, Gemma, Camino-López, Sandra, Díez-Caballero, Alberto, Ballesta-López, Carlos, Ybarra, Juan, Moscatiello, Fabrizio, Herrero, Javier, Badimon, Lina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848661/ https://www.ncbi.nlm.nih.gov/pubmed/24040759 http://dx.doi.org/10.1186/1471-2164-14-625 |
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