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Space-efficient and exact de Bruijn graph representation based on a Bloom filter
BACKGROUND: The de Bruijn graph data structure is widely used in next-generation sequencing (NGS). Many programs, e.g. de novo assemblers, rely on in-memory representation of this graph. However, current techniques for representing the de Bruijn graph of a human genome require a large amount of memo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848682/ https://www.ncbi.nlm.nih.gov/pubmed/24040893 http://dx.doi.org/10.1186/1748-7188-8-22 |