Rate-dependent Ca(2+) signalling underlying the force-frequency response in rat ventricular myocytes: a coupled electromechanical modeling study

BACKGROUND: Rate-dependent effects on the Ca(2+) sub-system in a rat ventricular myocyte are investigated. Here, we employ a deterministic mathematical model describing various Ca(2+) signalling pathways under voltage clamp (VC) conditions, to better understand the important role of calmodulin (CaM)...

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Detalles Bibliográficos
Autores principales: Krishna, Abhilash, Valderrábano, Miguel, Palade, Philip T, Clark, John W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848742/
https://www.ncbi.nlm.nih.gov/pubmed/24020888
http://dx.doi.org/10.1186/1742-4682-10-54

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