Lysophosphatidylcholine Triggers TLR2- and TLR4-Mediated Signaling Pathways but Counteracts LPS-Induced NO Synthesis in Peritoneal Macrophages by Inhibiting NF-κB Translocation and MAPK/ERK Phosphorylation

BACKGROUND: Lysophosphatidylcholine (LPC) is the main phospholipid component of oxidized low-density lipoprotein (oxLDL) and is usually noted as a marker of several human diseases, such as atherosclerosis, cancer and diabetes. Some studies suggest that oxLDL modulates Toll-like receptor (TLR) signal...

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Detalles Bibliográficos
Autores principales: Carneiro, Alan Brito, Iaciura, Bruna Maria Ferreira, Nohara, Lilian Lie, Lopes, Carla Duque, Veas, Esteban Mauricio Cordero, Mariano, Vania Sammartino, Bozza, Patricia Torres, Lopes, Ulisses Gazos, Atella, Georgia Correa, Almeida, Igor Correia, Silva-Neto, Mário Alberto Cardoso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848743/
https://www.ncbi.nlm.nih.gov/pubmed/24312681
http://dx.doi.org/10.1371/journal.pone.0076233

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