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A new approach to design safe CNTs with an understanding of redox potential

BACKGROUND: Carbon nanotubes (CNTs) are being increasingly industrialized and applied for various products. As of today, although several toxicological evaluations of CNTs have been conducted, designing safer CNTs is not practiced because reaction kinetics of CNTs with bioactive species is not fully...

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Detalles Bibliográficos
Autores principales: Tsuruoka, Shuji, Cassee, Flemming R, Castranova, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848781/
https://www.ncbi.nlm.nih.gov/pubmed/24004820
http://dx.doi.org/10.1186/1743-8977-10-44
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author Tsuruoka, Shuji
Cassee, Flemming R
Castranova, Vincent
author_facet Tsuruoka, Shuji
Cassee, Flemming R
Castranova, Vincent
author_sort Tsuruoka, Shuji
collection PubMed
description BACKGROUND: Carbon nanotubes (CNTs) are being increasingly industrialized and applied for various products. As of today, although several toxicological evaluations of CNTs have been conducted, designing safer CNTs is not practiced because reaction kinetics of CNTs with bioactive species is not fully understood. RESULTS: The authors propose a kinetic mechanism to establish designing safe CNTs as a new goal. According to a literature search on the behavior of CNTs and the effects of impurities, it is found that chemical reactions on CNT surface are attributed to redox reactions involving metal impurities and carbon structures at the CNT surface. CONCLUSION: A new goal is proposed to design safer CNTs using the redox potential hypothesis. The value of this hypothesis must be practically investigated and proven through the further experiments.
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spelling pubmed-38487812013-12-04 A new approach to design safe CNTs with an understanding of redox potential Tsuruoka, Shuji Cassee, Flemming R Castranova, Vincent Part Fibre Toxicol Commentary BACKGROUND: Carbon nanotubes (CNTs) are being increasingly industrialized and applied for various products. As of today, although several toxicological evaluations of CNTs have been conducted, designing safer CNTs is not practiced because reaction kinetics of CNTs with bioactive species is not fully understood. RESULTS: The authors propose a kinetic mechanism to establish designing safe CNTs as a new goal. According to a literature search on the behavior of CNTs and the effects of impurities, it is found that chemical reactions on CNT surface are attributed to redox reactions involving metal impurities and carbon structures at the CNT surface. CONCLUSION: A new goal is proposed to design safer CNTs using the redox potential hypothesis. The value of this hypothesis must be practically investigated and proven through the further experiments. BioMed Central 2013-09-02 /pmc/articles/PMC3848781/ /pubmed/24004820 http://dx.doi.org/10.1186/1743-8977-10-44 Text en Copyright © 2013 Tsuruoka et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Tsuruoka, Shuji
Cassee, Flemming R
Castranova, Vincent
A new approach to design safe CNTs with an understanding of redox potential
title A new approach to design safe CNTs with an understanding of redox potential
title_full A new approach to design safe CNTs with an understanding of redox potential
title_fullStr A new approach to design safe CNTs with an understanding of redox potential
title_full_unstemmed A new approach to design safe CNTs with an understanding of redox potential
title_short A new approach to design safe CNTs with an understanding of redox potential
title_sort new approach to design safe cnts with an understanding of redox potential
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848781/
https://www.ncbi.nlm.nih.gov/pubmed/24004820
http://dx.doi.org/10.1186/1743-8977-10-44
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