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miR-204 mediated loss of Myeloid cell leukemia-1 results in pancreatic cancer cell death

BACKGROUND: Pancreatic cancer is one of the most lethal human malignancies, with an all-stage 5-year survival of <5%, mainly due to lack of effective available therapies. Cancer cell survival is dependent upon up-regulation of the pro-survival response, mediated by anti-apoptotic proteins such as...

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Detalles Bibliográficos
Autores principales: Chen, Zhiyu, Sangwan, Veena, Banerjee, Sulagna, Mackenzie, Tiffany, Dudeja, Vikas, Li, Xiaowu, Wang, Huaizhi, Vickers, Selwyn M, Saluja, Ashok K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848798/
https://www.ncbi.nlm.nih.gov/pubmed/24025188
http://dx.doi.org/10.1186/1476-4598-12-105

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