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Molecular dynamics simulations on the Tre1 G protein-coupled receptor: exploring the role of the arginine of the NRY motif in Tre1 structure

BACKGROUND: The arginine of the D/E/NRY motif in Rhodopsin family G protein-coupled receptors (GPCRs) is conserved in 96% of these proteins. In some GPCRs, this arginine in transmembrane 3 can form a salt bridge with an aspartic acid or glutamic acid in transmembrane 6. The Drosophila melanogaster G...

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Detalles Bibliográficos
Autores principales: Pruitt, Margaret M, Lamm, Monica H, Coffman, Clark R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848830/
https://www.ncbi.nlm.nih.gov/pubmed/24044607
http://dx.doi.org/10.1186/1472-6807-13-15