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Transcriptome profiling reveals links between ParS/ParR, MexEF-OprN, and quorum sensing in the regulation of adaptation and virulence in Pseudomonas aeruginosa

BACKGROUND: The ParS/ParR two component regulatory system plays critical roles for multidrug resistance in Pseudomonas aeruginosa. It was demonstrated that in the presence of antimicrobials, ParR enhances bacterial survival by distinct mechanisms including activation of the mexXY efflux genes, enhan...

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Detalles Bibliográficos
Autores principales: Wang, Dongping, Seeve, Candace, Pierson, Leland S, Pierson, Elizabeth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848899/
https://www.ncbi.nlm.nih.gov/pubmed/24034668
http://dx.doi.org/10.1186/1471-2164-14-618