YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells

BACKGROUND: The brain cancer stem cell (CSC) model describes a small subset of glioma cells as being responsible for tumor initiation, conferring therapy resistance and tumor recurrence. In brain CSC, the PI3-K/AKT and the RAS/mitogen activated protein kinase (MAPK) pathways are found to be activate...

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Detalles Bibliográficos
Autores principales: Mantwill, Klaus, Naumann, Ulrike, Seznec, Janina, Girbinger, Vroni, Lage, Hermann, Surowiak, Pawel, Beier, Dagmar, Mittelbronn, Michel, Schlegel, Jürgen, Holm, Per Sonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848904/
https://www.ncbi.nlm.nih.gov/pubmed/24044901
http://dx.doi.org/10.1186/1479-5876-11-216

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