Histone deacetylase (HDAC) inhibitory and antiproliferative activities of phenolic-rich extracts derived from the rhizome of Hydnophytum formicarum Jack.: sinapinic acid acts as HDAC inhibitor

BACKGROUND: The rhizome of Hydnophytum formicarum Jack., a medicinal plant known in Thai as Hua-Roi-Roo, has been used in Thai traditional herbal medicine for treatment of cancer. We assessed the ability of its ethanolic and phenolic-rich extracts and its major phenolic compound, sinapinic acid, pos...

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Detalles Bibliográficos
Autores principales: Senawong, Thanaset, Misuna, Suwatchai, Khaopha, Somprasong, Nuchadomrong, Suporn, Sawatsitang, Prasan, Phaosiri, Chanokbhorn, Surapaitoon, Arpa, Sripa, Banchob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848914/
https://www.ncbi.nlm.nih.gov/pubmed/24053181
http://dx.doi.org/10.1186/1472-6882-13-232

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