Cargando…

Metastatic colorectal cancer first-line treatment with bevacizumab: the impact of K-ras mutation

BACKGROUND: Bevacizumab plus chemotherapy prolongs progression-free survival (PFS) and overall survival (OS) in metastatic colorectal cancer (mCRC). Although there is strong evidence to suggest that the mutational status of the K-ras oncogene has a role as a predictive factor for activity in patient...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rossi, Luigi, Veltri, Enzo, Zullo, Angelo, Zoratto, Federica, Colonna, Maria, Longo, Flavia, Mottolese, Marcella, Giannarelli, Diana, Ruco, Luigi, Marchetti, Paolo, Romiti, Adriana, Barucca, Viola, Giannini, Giuseppe, Bianchi, Loredana, Tomao, Silverio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848929/ https://www.ncbi.nlm.nih.gov/pubmed/24348051 http://dx.doi.org/10.2147/OTT.S43828

Ejemplares similares

Critical appraisal of bevacizumab in the treatment of metastatic colorectal cancer
por: Zoratto, Federica, et al.
Publicado: (2012)

Chemotherapy and target therapy as neo-adjuvant approach for initially unresectable colorectal liver metastases
por: Rossi, Luigi, et al.
Publicado: (2012)

Positron Emission Tomography (PET) radiotracers in oncology – utility of 18F-Fluoro-deoxy-glucose (FDG)-PET in the management of patients with non-small-cell lung cancer (NSCLC)
por: Miele, Evelina, et al.
Publicado: (2008)

Current status of bevacizumab in advanced ovarian cancer
por: Tomao, Federica, et al.
Publicado: (2013)

The synchronous occurrence of squamous cell carcinoma and gastrointestinal stromal tumor (GIST) at esophageal site
por: Spinelli, Gian Paolo, et al.
Publicado: (2008)

Angiogenesis and antiangiogenic agents in cervical cancer
por: Tomao, Federica, et al.
Publicado: (2014)

A phase II trial of a biweekly combination of paclitaxel and gemcitabine in metastatic breast cancer
por: Tomao, Silverio, et al.
Publicado: (2006)

Bevacizumab in ovarian cancer: A critical review of phase III studies
por: Rossi, Luigi, et al.
Publicado: (2016)

Efficacy and safety analysis of once per cycle pegfilgrastim and daily lenograstim in patients with breast cancer receiving adjuvant myelosuppressive chemotherapy FEC 100: a pilot study
por: Rossi, Luigi, et al.
Publicado: (2013)

Factors influencing choice of chemotherapy in metastatic colorectal cancer (mCRC)
por: Rossi, Luigi, et al.
Publicado: (2013)

Triple-negative breast cancer: new perspectives for targeted therapies
por: Tomao, Federica, et al.
Publicado: (2015)

Emerging role of cancer stem cells in the biology and treatment of ovarian cancer: basic knowledge and therapeutic possibilities for an innovative approach
por: Tomao, Federica, et al.
Publicado: (2013)

Gemcitabine-oxaliplatin (GEMOX) as salvage treatment in pretreated epithelial ovarian cancer patients
por: Vici, Patrizia, et al.
Publicado: (2013)

Neoadjuvant Sequential Docetaxel Followed by High‐Dose Epirubicin in Combination With Cyclophosphamide Administered Concurrently With Trastuzumab. The DECT Trial
por: Pizzuti, Laura, et al.
Publicado: (2016)

Helicobacter pylori infection and gastroesophageal cancer: unveiling a Hamletic dilemma
por: Zullo, Angelo, et al.
Publicado: (2014)

The Pathogenetic Role of the HGF/c-Met System in Papillary Carcinoma of the Thyroid
por: Ruco, Luigi, et al.
Publicado: (2014)

Lack of HXK2 Induces Localization of Active Ras in Mitochondria and Triggers Apoptosis in the Yeast Saccharomyces cerevisiae
por: Amigoni, Loredana, et al.
Publicado: (2013)

RAS Mutation Conversion in Bevacizumab-Treated Metastatic Colorectal Cancer Patients: A Liquid Biopsy Based Study
por: Nicolazzo, Chiara, et al.
Publicado: (2022)

Occurence of RAS reversion in metastatic colorectal cancer patients treated with bevacizumab
por: Epistolio, Samantha, et al.
Publicado: (2021)

Investigating Molecular Profiles of Ovarian Cancer: An Update on Cancer Stem Cells
por: Tomao, Federica, et al.
Publicado: (2014)

Alectinib in the treatment of ocular metastases of ALK rearranged non small cell lung cancer: Description of 2 case reports
por: Gozzi, Elisa, et al.
Publicado: (2020)

Herpes zoster granulomatous dermatitis in metastatic lung cancer treated with nivolumab: A case report
por: Gozzi, Elisa, et al.
Publicado: (2020)

Differential Localization of VE- and N-Cadherins in Human Endothelial Cells: VE-Cadherin Competes with N-Cadherin for Junctional Localization
por: Navarro, Pilar, et al.
Publicado: (1998)

Myopericytoma-like tumors of the lung: Report of two cases
por: Lombardi, Mariangela, et al.
Publicado: (2021)

Oxidative Stress Posttranslationally Regulates the Expression of Ha-Ras and Ki-Ras in Cultured Astrocytes
por: Messina, Samantha, et al.
Publicado: (2012)

An unusual case of spleen metastasis from carcinoma ex pleomorphic adenoma of the parotid gland
por: Rossi, Luigi, et al.
Publicado: (2014)

Bone metastases from bladder perivascular epithelioid cell tumor – an unusual localization of a rare tumor: a case report
por: Palleschi, Giovanni, et al.
Publicado: (2014)

Update on Poly-ADP-ribose polymerase inhibition for ovarian cancer treatment
por: Papa, Anselmo, et al.
Publicado: (2016)

Immunologic treatments for precancerous lesions and uterine cervical cancer
por: Vici, Patrizia, et al.
Publicado: (2014)

Albumin-bound formulation of paclitaxel (Abraxane(®) ABI-007) in the treatment of breast cancer
por: Miele, Evelina, et al.
Publicado: (2009)

Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy
por: Miele, Evelina, et al.
Publicado: (2012)

Capecitabine and Temozolomide (CAPTEM) in Advanced Neuroendocrine Neoplasms (NENs): A Systematic Review and Pooled Analysis
por: Arrivi, Giulia, et al.
Publicado: (2022)

Aflibercept or bevacizumab in combination with FOLFIRI as second-line treatment of mRAS metastatic colorectal cancer patients: the ARBITRATION study protocol
por: Ottaiano, Alessandro, et al.
Publicado: (2021)

Survival of hereditary non-polyposis colorectal cancer patients compared with sporadic colorectal cancer patients
por: Stigliano, Vittoria, et al.
Publicado: (2008)

Emerging Role of PARP Inhibitors in Metastatic Triple Negative Breast Cancer. Current Scenario and Future Perspectives
por: Barchiesi, Giacomo, et al.
Publicado: (2021)

Transient Disappearance of RAS Mutant Clones in Plasma: A Counterintuitive Clinical Use of EGFR Inhibitors in RAS Mutant Metastatic Colorectal Cancer
por: Raimondi, Cristina, et al.
Publicado: (2019)

Evaluating the Optimal Sequence of Treatment With EGFR Inhibitors and Bevacizumab in RAS Wild-Type Metastatic Colorectal Cancer
por: Martins, Diana, et al.
Publicado: (2022)

Efficacy and safety analysis of bevacizumab combined with capecitabine in the maintenance treatment of RAS‐mutant metastatic colorectal cancer
por: Huang, Weizhen, et al.
Publicado: (2022)

Pemetrexed as first-line therapy for non-squamous non-small cell lung cancer
por: Ricciardi, Serena, et al.
Publicado: (2009)

A 17-Gene Expression Signature for Early Identification of Poor Prognosis in Clear Cell Renal Cell Carcinoma
por: Bassanelli, Maria, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kf5sqr2jc0cjf2t22jdf3e03bl