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Contribution of different pneumococcal virulence factors to experimental meningitis in mice

BACKGROUND: Pneumococcal meningitis (PM) is a life-threatening disease with a high case-fatality rate and elevated risk for serious neurological sequelae. In this study, we investigated the contribution of three major virulence factors of Streptococcus pneumoniae, the capsule, pneumococcal surface p...

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Detalles Bibliográficos
Autores principales: Ricci, Susanna, Gerlini, Alice, Pammolli, Andrea, Chiavolini, Damiana, Braione, Velia, Tripodi, Sergio Antonio, Colombari, Bruna, Blasi, Elisabetta, Oggioni, Marco Rinaldo, Peppoloni, Samuele, Pozzi, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848944/
https://www.ncbi.nlm.nih.gov/pubmed/24059458
http://dx.doi.org/10.1186/1471-2334-13-444