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Plant proteolytic enzyme papain abrogates angiogenic activation of human umbilical vein endothelial cells (HUVEC) in vitro

BACKGROUND: Vascular endothelial growth factor (VEGF) is a key regulator of physiologic and pathogenic angiogenesis in diseases such as cancer and diabetic retinopathy. It is known that cysteine proteases from plants, like bromelain and papain are capable to suppress inflammatory activation. Recent...

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Detalles Bibliográficos
Autores principales: Mohr, Thomas, Desser, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849051/
https://www.ncbi.nlm.nih.gov/pubmed/24053149
http://dx.doi.org/10.1186/1472-6882-13-231