PRICKLE1 Interaction with SYNAPSIN I Reveals a Role in Autism Spectrum Disorders

The frequent comorbidity of Autism Spectrum Disorders (ASDs) with epilepsy suggests a shared underlying genetic susceptibility; several genes, when mutated, can contribute to both disorders. Recently, PRICKLE1 missense mutations were found to segregate with ASD. However, the mechanism by which mutat...

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Detalles Bibliográficos
Autores principales: Paemka, Lily, Mahajan, Vinit B., Skeie, Jessica M., Sowers, Levi P., Ehaideb, Salleh N., Gonzalez-Alegre, Pedro, Sasaoka, Toshikuni, Tao, Hirotaka, Miyagi, Asuka, Ueno, Naoto, Takao, Keizo, Miyakawa, Tsuyoshi, Wu, Shu, Darbro, Benjamin W., Ferguson, Polly J., Pieper, Andrew A., Britt, Jeremiah K., Wemmie, John A., Rudd, Danielle S., Wassink, Thomas, El-Shanti, Hatem, Mefford, Heather C., Carvill, Gemma L., Manak, J. Robert, Bassuk, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849077/
https://www.ncbi.nlm.nih.gov/pubmed/24312498
http://dx.doi.org/10.1371/journal.pone.0080737

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