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Central Role for MCP-1/CCL2 in Injury-Induced Inflammation Revealed by In Vitro, In Silico, and Clinical Studies

The translation of in vitro findings to clinical outcomes is often elusive. Trauma/hemorrhagic shock (T/HS) results in hepatic hypoxia that drives inflammation. We hypothesize that in silico methods would help bridge in vitro hepatocyte data and clinical T/HS, in which the liver is a primary site of...

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Detalles Bibliográficos
Autores principales: Ziraldo, Cordelia, Vodovotz, Yoram, Namas, Rami A., Almahmoud, Khalid, Tapias, Victor, Mi, Qi, Barclay, Derek, Jefferson, Bahiyyah S., Chen, Guoqiang, Billiar, Timothy R., Zamora, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849193/
https://www.ncbi.nlm.nih.gov/pubmed/24312451
http://dx.doi.org/10.1371/journal.pone.0079804