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Downregulation of KPNA2 in non-small-cell lung cancer is associated with Oct4 expression
BACKGROUND: Oct4 is a major transcription factor related to stem cell self-renewal and differentiation. To fulfill its functions, it must be able to enter the nucleus and remain there to affect transcription. KPNA2, a member of the karyopherin family, plays a central role in nucleocytoplasmic transp...
Autores principales: | Li, Xiao-Lei, Jia, Lan-Ling, Shi, Mu-Mu, Li, Xin, Li, Zhong-Hua, Li, Hui-Feng, Wang, En-Hua, Jia, Xin-Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849263/ https://www.ncbi.nlm.nih.gov/pubmed/24070213 http://dx.doi.org/10.1186/1479-5876-11-232 |
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