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A physiologically-based flow network model for hepatic drug elimination I: regular lattice lobule model
We develop a physiologically-based lattice model for the transport and metabolism of drugs in the functional unit of the liver, called the lobule. In contrast to earlier studies, we have emphasized the dominant role of convection in well-vascularized tissue with a given structure. Estimates of conve...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849449/ https://www.ncbi.nlm.nih.gov/pubmed/24007328 http://dx.doi.org/10.1186/1742-4682-10-52 |