Endometrioid adenocarcinoma with simultaneous endocervical and intestinal-type mucinous differentiation: report of a rare phenomenon and the immunohistochemical profile

ABSTRACT: Intestinal differentiation in the endometrium is rare with only case reports in the international literature. We describe a case of simultaneous endocervical and intestinal-type mucinous differentiation with goblet cells arising in a FIGO grade 1 endometrioid adenocarcinoma. The patient ha...

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Autores principales: Buell-Gutbrod, Rebecca, Sung, C James, Lawrence, W Dwayne, Quddus, M Ruhul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849525/
https://www.ncbi.nlm.nih.gov/pubmed/23915109
http://dx.doi.org/10.1186/1746-1596-8-128
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author Buell-Gutbrod, Rebecca
Sung, C James
Lawrence, W Dwayne
Quddus, M Ruhul
author_facet Buell-Gutbrod, Rebecca
Sung, C James
Lawrence, W Dwayne
Quddus, M Ruhul
author_sort Buell-Gutbrod, Rebecca
collection PubMed
description ABSTRACT: Intestinal differentiation in the endometrium is rare with only case reports in the international literature. We describe a case of simultaneous endocervical and intestinal-type mucinous differentiation with goblet cells arising in a FIGO grade 1 endometrioid adenocarcinoma. The patient had no involvement of the myometrium, cervix, or extra-uterine sites. There were no intestinal metaplastic changes of the endocervical canal. The etiology of this change is unknown, although recent reports suggest an association with hyperestrogenism. VIRTUAL SLIDES: The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1209512176931698
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spelling pubmed-38495252013-12-05 Endometrioid adenocarcinoma with simultaneous endocervical and intestinal-type mucinous differentiation: report of a rare phenomenon and the immunohistochemical profile Buell-Gutbrod, Rebecca Sung, C James Lawrence, W Dwayne Quddus, M Ruhul Diagn Pathol Case Report ABSTRACT: Intestinal differentiation in the endometrium is rare with only case reports in the international literature. We describe a case of simultaneous endocervical and intestinal-type mucinous differentiation with goblet cells arising in a FIGO grade 1 endometrioid adenocarcinoma. The patient had no involvement of the myometrium, cervix, or extra-uterine sites. There were no intestinal metaplastic changes of the endocervical canal. The etiology of this change is unknown, although recent reports suggest an association with hyperestrogenism. VIRTUAL SLIDES: The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1209512176931698 BioMed Central 2013-08-02 /pmc/articles/PMC3849525/ /pubmed/23915109 http://dx.doi.org/10.1186/1746-1596-8-128 Text en Copyright © 2013 Buell-Gutbrod et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Buell-Gutbrod, Rebecca
Sung, C James
Lawrence, W Dwayne
Quddus, M Ruhul
Endometrioid adenocarcinoma with simultaneous endocervical and intestinal-type mucinous differentiation: report of a rare phenomenon and the immunohistochemical profile
title Endometrioid adenocarcinoma with simultaneous endocervical and intestinal-type mucinous differentiation: report of a rare phenomenon and the immunohistochemical profile
title_full Endometrioid adenocarcinoma with simultaneous endocervical and intestinal-type mucinous differentiation: report of a rare phenomenon and the immunohistochemical profile
title_fullStr Endometrioid adenocarcinoma with simultaneous endocervical and intestinal-type mucinous differentiation: report of a rare phenomenon and the immunohistochemical profile
title_full_unstemmed Endometrioid adenocarcinoma with simultaneous endocervical and intestinal-type mucinous differentiation: report of a rare phenomenon and the immunohistochemical profile
title_short Endometrioid adenocarcinoma with simultaneous endocervical and intestinal-type mucinous differentiation: report of a rare phenomenon and the immunohistochemical profile
title_sort endometrioid adenocarcinoma with simultaneous endocervical and intestinal-type mucinous differentiation: report of a rare phenomenon and the immunohistochemical profile
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849525/
https://www.ncbi.nlm.nih.gov/pubmed/23915109
http://dx.doi.org/10.1186/1746-1596-8-128
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