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Combined blockade of HER2 and VEGF exerts greater growth inhibition of HER2-overexpressing gastric cancer xenografts than individual blockade
Gastric cancer overexpressing the human epidermal growth factor 2 (HER2) protein has a poor outcome, although a combination of chemotherapy and the anti-HER2 antibody trastuzumab has been approved for the treatment of advanced gastric cancer. Vascular endothelial growth factor (VEGF) expression in g...
Autores principales: | Singh, Rohit, Kim, Woo Jin, Kim, Pyeung-Hyeun, Hong, Hyo Jeong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849567/ https://www.ncbi.nlm.nih.gov/pubmed/24176949 http://dx.doi.org/10.1038/emm.2013.111 |
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