Pioglitazone counteracts the tumor necrosis factor-α inhibition of follicle-stimulating hormone-induced follicular development and estradiol production in an in vitro mouse preantral follicle culture system

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age and is characterized by chronic anovulation. Insulin resistance may be a key component of the pathogenesis of this disorder. Pioglitazone is a thiazolidinedione derivative that acts by improving...

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Detalles Bibliográficos
Autores principales: Hara, Shuichiro, Takahashi, Toshifumi, Amita, Mitsuyoshi, Matsuo, Koki, Igarashi, Hideki, Kurachi, Hirohisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849627/
https://www.ncbi.nlm.nih.gov/pubmed/24079935
http://dx.doi.org/10.1186/1757-2215-6-69

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