Cargando…
Deregulated expression of TANK in glioblastomas triggers pro-tumorigenic ERK1/2 and AKT signaling pathways
Signal transmission by the noncanonical IkappaB kinases (IKKs), TANK-binding kinase 1 (TBK1) and IKKɛ, requires interaction with adapter proteins such as TRAF associated NF-κB activator (TANK). Although increased expression or dysregulation of both kinases has been described for a variety of human c...
Autores principales: | Stellzig, J, Chariot, A, Shostak, K, Ismail Göktuna, S, Renner, F, Acker, T, Pagenstecher, A, Schmitz, M L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849693/ https://www.ncbi.nlm.nih.gov/pubmed/24217713 http://dx.doi.org/10.1038/oncsis.2013.42 |
Ejemplares similares
-
IKBKE-driven TPL2 and MEK1 phosphorylations sustain constitutive ERK1/2 activation in tumor cells
por: Göktuna, Serkan Ismail
Publicado: (2022) -
NF-κB, stem cells and breast cancer: the links get stronger
por: Shostak, Kateryna, et al.
Publicado: (2011) -
NF-κB-induced KIAA1199 promotes survival through EGFR signalling
por: Shostak, Kateryna, et al.
Publicado: (2014) -
Serglycin activates pro-tumorigenic signaling and controls glioblastoma cell stemness, differentiation and invasive potential
por: Manou, Dimitra, et al.
Publicado: (2020) -
CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic
por: Marshall, A D, et al.
Publicado: (2017)