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Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling
The metazoan Hippo pathway is an essential tumour suppressor signalling cascade that ensures normal tissue growth by co-ordinating cell proliferation, cell death and cell differentiation. Over the past years, various genetic and biochemical studies in Drosophila and mammals have defined a conserved...
Autor principal: | Hergovich, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849777/ https://www.ncbi.nlm.nih.gov/pubmed/23985307 http://dx.doi.org/10.1186/2045-3701-3-32 |
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