Cargando…

Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitro usage of alternative coreceptors during progressive HIV-1 subtype C infection

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) subtype C (C-HIV) is spreading rapidly and is now responsible for >50% of HIV-1 infections worldwide, and >95% of infections in southern Africa and central Asia. These regions are burdened with the overwhelming majority of HIV-1 infection...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cashin, Kieran, Jakobsen, Martin R, Sterjovski, Jasminka, Roche, Michael, Ellett, Anne, Flynn, Jacqueline K, Borm, Katharina, Gouillou, Maelenn, Churchill, Melissa J, Gorry, Paul R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849974/ https://www.ncbi.nlm.nih.gov/pubmed/24041034 http://dx.doi.org/10.1186/1742-4690-10-98

Ejemplares similares

Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection
por: Jakobsen, Martin R., et al.
Publicado: (2013)

CoRSeq(V3-C): a novel HIV-1 subtype C specific V3 sequence based coreceptor usage prediction algorithm
por: Cashin, Kieran, et al.
Publicado: (2013)

Covariance of Charged Amino Acids at Positions 322 and 440 of HIV-1 Env Contributes to Coreceptor Specificity of Subtype B Viruses, and Can Be Used to Improve the Performance of V3 Sequence-Based Coreceptor Usage Prediction Algorithms
por: Cashin, Kieran, et al.
Publicado: (2014)

Quantifying Susceptibility of CD4(+) Stem Memory T-Cells to Infection by Laboratory Adapted and Clinical HIV-1 Strains
por: Flynn, Jacqueline K., et al.
Publicado: (2014)

Differences in coreceptor specificity contribute to alternative tropism of HIV-1 subtype C for CD4(+) T-cell subsets, including stem cell memory T-cells
por: Cashin, Kieran, et al.
Publicado: (2014)

Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc
por: Borm, Katharina, et al.
Publicado: (2016)

Endocytosis and Recycling of the HIV Coreceptor Ccr5
por: Signoret, Nathalie, et al.
Publicado: (2000)

Reliable Genotypic Tropism Tests for the Major HIV-1 Subtypes
por: Cashin, Kieran, et al.
Publicado: (2015)

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS
por: Sterjovski, Jasminka, et al.
Publicado: (2007)

HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry
por: Roche, Michael, et al.
Publicado: (2011)

Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues
por: Gray, Lachlan, et al.
Publicado: (2011)

HIV-2 interaction with cell coreceptors: amino acids within the V1/V2 region of viral envelope are determinant for CCR8, CCR5 and CXCR4 usage
por: Santos-Costa, Quirina, et al.
Publicado: (2014)

Clinical significance of HIV-1 coreceptor usage
por: Schuitemaker, Hanneke, et al.
Publicado: (2011)

A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations
por: Roche, Michael, et al.
Publicado: (2013)

Distinct HIV-1 entry phenotypes are associated with transmission, subtype specificity, and resistance to broadly neutralizing antibodies
por: Chikere, Kelechi, et al.
Publicado: (2014)

Loss of CXCR6 coreceptor usage characterizes pathogenic lentiviruses
por: Wetzel, Katherine S., et al.
Publicado: (2018)

Site-Selective Solid-Phase Synthesis of a CCR5 Sulfopeptide Library To Interrogate HIV Binding and Entry
por: Liu, Xuyu, et al.
Publicado: (2014)

HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector
por: Anderson, Joseph, et al.
Publicado: (2005)

Analysis of Physicochemical and Structural Properties Determining HIV-1 Coreceptor Usage
por: Bozek, Katarzyna, et al.
Publicado: (2013)

Predicted HIV-1 coreceptor usage among Kenya patients shows a high tendency for subtype d to be cxcr4 tropic
por: Wambui, Veronica, et al.
Publicado: (2012)

Association Between HIV-1 Coreceptor Usage and Resistance to Broadly Neutralizing Antibodies
por: Pfeifer, Nico, et al.
Publicado: (2014)

HIV-1 Coreceptor Usage Assessment by Ultra-Deep Pyrosequencing and Response to Maraviroc
por: Rodriguez, Christophe, et al.
Publicado: (2015)

HIV-1 coreceptor usage prediction without multiple alignments: an application of string kernels
por: Boisvert, Sébastien, et al.
Publicado: (2008)

Molecular Epidemiology of HIV-1 in Ghana: Subtype Distribution, Drug Resistance and Coreceptor Usage
por: Appah, Anna, et al.
Publicado: (2022)

Evolution of DC-SIGN use revealed by fitness studies of R5 HIV-1 variants emerging during AIDS progression
por: Borggren, Marie, et al.
Publicado: (2008)

Resistance to the CCR5 Inhibitor 5P12-RANTES Requires a Difficult Evolution from CCR5 to CXCR4 Coreceptor Use
por: Nedellec, Rebecca, et al.
Publicado: (2011)

Structural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage
por: Sander, Oliver, et al.
Publicado: (2007)

The Variable Loop 3 in the Envelope Glycoprotein Is Critical for the Atypical Coreceptor Usage of an HIV-1 Strain
por: Xiang, Yue, et al.
Publicado: (2014)

Genetic variation within the gene encoding the HIV-1 CCR5 coreceptor in two South African populations
por: Picton, Anabela C.P., et al.
Publicado: (2010)

Identifying CCR5 coreceptor populations permissive for HIV-1 entry and productive infection: implications for in vivo studies
por: Weichseldorfer, Matthew, et al.
Publicado: (2022)

Evolution of Multiple Domains of the HIV-1 Envelope Glycoprotein during Coreceptor Switch with CCR5 Antagonist Therapy
por: Du, Yueqi, et al.
Publicado: (2022)

Understanding the mechanisms driving the spread of subtype C HIV-1
por: Gartner, Matthew J., et al.
Publicado: (2020)

Increased Sensitivity to Broadly Neutralizing Antibodies of End-Stage Disease R5 HIV-1 Correlates with Evolution in Env Glycosylation and Charge
por: Borggren, Marie, et al.
Publicado: (2011)

Improving HIV coreceptor usage prediction in the clinic using hints from next-generation sequencing data
por: Pfeifer, Nico, et al.
Publicado: (2012)

Modeling of CCR5 Recognition by HIV-1 gp120: How the Viral Protein Exploits the Conformational Plasticity of the Coreceptor
por: Jacquemard, Célien, et al.
Publicado: (2021)

Evolution of coreceptor utilization to escape CCR5 antagonist therapy
por: Zhang, Jie, et al.
Publicado: (2016)

Tracking coreceptor switch of the transmitted/founder HIV-1 identifies co-evolution of HIV-1 antigenicity, coreceptor usage and CD4 subset targeting: the RV217 acute infection cohort study
por: Marichannegowda, Manukumar Honnayakanahalli, et al.
Publicado: (2023)

HIV Coreceptor Downregulation as Antiviral Principle: SDF-1α–dependent Internalization of the Chemokine Receptor CXCR4 Contributes to Inhibition of HIV Replication
por: Amara, Ali, et al.
Publicado: (1997)

Highly Accurate Structure-Based Prediction of HIV-1 Coreceptor Usage Suggests Intermolecular Interactions Driving Tropism
por: Kieslich, Chris A., et al.
Publicado: (2016)

A genotypic method for determining HIV-2 coreceptor usage enables epidemiological studies and clinical decision support
por: Döring, Matthias, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_r829cpvnd8p61knjn4cgho2gma