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Immune ambivalence: The schizophrenic bleomycin

In addition to cytotoxic effects, anticancer agents can exert multiple immunomodulatory functions. We have recently described the molecular mechanisms whereby bleomycin can 1) promote endoplasmic reticulum stress, causing the immunogenic death of cancer cells and hence strengthening antitumor CD8(+)...

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Detalles Bibliográficos
Autores principales: Mignot, Grégoire, Bugaut, Hélène, Ghiringhelli, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850019/
https://www.ncbi.nlm.nih.gov/pubmed/24327935
http://dx.doi.org/10.4161/onci.25737