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Immune ambivalence: The schizophrenic bleomycin
In addition to cytotoxic effects, anticancer agents can exert multiple immunomodulatory functions. We have recently described the molecular mechanisms whereby bleomycin can 1) promote endoplasmic reticulum stress, causing the immunogenic death of cancer cells and hence strengthening antitumor CD8(+)...
Autores principales: | Mignot, Grégoire, Bugaut, Hélène, Ghiringhelli, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850019/ https://www.ncbi.nlm.nih.gov/pubmed/24327935 http://dx.doi.org/10.4161/onci.25737 |
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