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Contribution of regulatory T cells to immunosuppression and disease progression in multiple myeloma patients

Multiple myeloma (MM) patients exhibit consistent degrees of immune dysfunction. Regulatory T cells contribute to the establishment of an immunosuppressive status in MM patients, hence favoring disease progression.

Detalles Bibliográficos
Autores principales: Raja, Karthick Raja Muthu, Hajek, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850022/
https://www.ncbi.nlm.nih.gov/pubmed/24327932
http://dx.doi.org/10.4161/onci.25619
Descripción
Sumario:Multiple myeloma (MM) patients exhibit consistent degrees of immune dysfunction. Regulatory T cells contribute to the establishment of an immunosuppressive status in MM patients, hence favoring disease progression.