Cargando…
Cathepsin C is a tissue-specific regulator of squamous carcinogenesis
Serine and cysteine cathepsin (Cts) proteases are an important class of intracellular and pericellular enzymes mediating multiple aspects of tumor development. Emblematic of these is CtsB, reported to play functionally significant roles during pancreatic islet and mammary carcinogenesis. CtsC, on th...
Autores principales: | Ruffell, Brian, Affara, Nesrine I., Cottone, Lucia, Junankar, Simon, Johansson, Magnus, DeNardo, David G., Korets, Lidiya, Reinheckel, Thomas, Sloane, Bonnie F., Bogyo, Mathew, Coussens, Lisa M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850093/ https://www.ncbi.nlm.nih.gov/pubmed/24065739 http://dx.doi.org/10.1101/gad.224899.113 |
Ejemplares similares
-
Differential Impact of Cysteine Cathepsins on Genetic Mouse Models of De novo Carcinogenesis: Cathepsin B as Emerging Therapeutic Target
por: Reinheckel, Thomas, et al.
Publicado: (2012) -
Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression
por: DeNardo, David G, et al.
Publicado: (2007) -
Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity
por: DeNardo, David G., et al.
Publicado: (2010) -
Cathepsin B & L Are Not Required for Ebola Virus Replication
por: Marzi, Andrea, et al.
Publicado: (2012) -
Low‐level lysosomal membrane permeabilization for limited release and sublethal functions of cathepsin proteases in the cytosol and nucleus
por: Reinheckel, Thomas, et al.
Publicado: (2022)