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Cause-specific telomere factors deregulation in hepatocellular carcinoma

BACKGROUND: Among the numerous genetic defects associated with hepatocarcinogenesis, telomere abnormalities appear to play a role both in tumor promotion and maintenance. Telomeres, the chromosome extremities, are protected by specific proteins, the shelterin complex and by additional factors. Besid...

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Detalles Bibliográficos
Autores principales: El Idrissi, Manale, Hervieu, Valérie, Merle, Philippe, Mortreux, Franck, Wattel, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850108/
https://www.ncbi.nlm.nih.gov/pubmed/24020493
http://dx.doi.org/10.1186/1756-9966-32-64

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