Cancer-associated fibroblasts and macrophages: Friendly conspirators for malignancy

Inflammation, which is now recognized as an hallmark of cancer, is intimately linked to the reactivity of stromal fibroblasts. Accumulating evidence indicate that cancer-associated fibroblasts not only drive the epithelial-mesenchymal transition and metabolically sustain the growth of cancer cells,...

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Detalles Bibliográficos
Autor principal: Chiarugi, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850271/
https://www.ncbi.nlm.nih.gov/pubmed/24319632
http://dx.doi.org/10.4161/onci.25563
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author Chiarugi, Paola
author_facet Chiarugi, Paola
author_sort Chiarugi, Paola
collection PubMed
description Inflammation, which is now recognized as an hallmark of cancer, is intimately linked to the reactivity of stromal fibroblasts. Accumulating evidence indicate that cancer-associated fibroblasts not only drive the epithelial-mesenchymal transition and metabolically sustain the growth of cancer cells, but also engage in a reciprocal relationship with M2 macrophages that dramatically boost malignancy.
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spelling pubmed-38502712013-12-06 Cancer-associated fibroblasts and macrophages: Friendly conspirators for malignancy Chiarugi, Paola Oncoimmunology Author's View Inflammation, which is now recognized as an hallmark of cancer, is intimately linked to the reactivity of stromal fibroblasts. Accumulating evidence indicate that cancer-associated fibroblasts not only drive the epithelial-mesenchymal transition and metabolically sustain the growth of cancer cells, but also engage in a reciprocal relationship with M2 macrophages that dramatically boost malignancy. Landes Bioscience 2013-09-01 2013-07-03 /pmc/articles/PMC3850271/ /pubmed/24319632 http://dx.doi.org/10.4161/onci.25563 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Chiarugi, Paola
Cancer-associated fibroblasts and macrophages: Friendly conspirators for malignancy
title Cancer-associated fibroblasts and macrophages: Friendly conspirators for malignancy
title_full Cancer-associated fibroblasts and macrophages: Friendly conspirators for malignancy
title_fullStr Cancer-associated fibroblasts and macrophages: Friendly conspirators for malignancy
title_full_unstemmed Cancer-associated fibroblasts and macrophages: Friendly conspirators for malignancy
title_short Cancer-associated fibroblasts and macrophages: Friendly conspirators for malignancy
title_sort cancer-associated fibroblasts and macrophages: friendly conspirators for malignancy
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850271/
https://www.ncbi.nlm.nih.gov/pubmed/24319632
http://dx.doi.org/10.4161/onci.25563
work_keys_str_mv AT chiarugipaola cancerassociatedfibroblastsandmacrophagesfriendlyconspiratorsformalignancy

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