Cargando…

Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus

Over the last decade, cytomegalovirus (CMV) has been suggested to promote the development of glioblastoma multiforme (GBM). Recent evidence demonstrates that CMV contributes to the progression of GBM in the context of oncosuppressor gene mutations. This finding provides further insights into the mec...

Descripción completa

Detalles Bibliográficos
Autores principales: Hollon, Todd C, Price, Richard L, Kwon, Chang-Hyuk, Chiocca, E Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850294/
https://www.ncbi.nlm.nih.gov/pubmed/24319635
http://dx.doi.org/10.4161/onci.25620
_version_ 1782294068404944896
author Hollon, Todd C
Price, Richard L
Kwon, Chang-Hyuk
Chiocca, E Antonio
author_facet Hollon, Todd C
Price, Richard L
Kwon, Chang-Hyuk
Chiocca, E Antonio
author_sort Hollon, Todd C
collection PubMed
description Over the last decade, cytomegalovirus (CMV) has been suggested to promote the development of glioblastoma multiforme (GBM). Recent evidence demonstrates that CMV contributes to the progression of GBM in the context of oncosuppressor gene mutations. This finding provides further insights into the mechanisms whereby CMV exacerbates the malignancy of GBM.
format Online
Article
Text
id pubmed-3850294
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Landes Bioscience
record_format MEDLINE/PubMed
spelling pubmed-38502942013-12-06 Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus Hollon, Todd C Price, Richard L Kwon, Chang-Hyuk Chiocca, E Antonio Oncoimmunology Author's View Over the last decade, cytomegalovirus (CMV) has been suggested to promote the development of glioblastoma multiforme (GBM). Recent evidence demonstrates that CMV contributes to the progression of GBM in the context of oncosuppressor gene mutations. This finding provides further insights into the mechanisms whereby CMV exacerbates the malignancy of GBM. Landes Bioscience 2013-09-01 2013-07-09 /pmc/articles/PMC3850294/ /pubmed/24319635 http://dx.doi.org/10.4161/onci.25620 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Hollon, Todd C
Price, Richard L
Kwon, Chang-Hyuk
Chiocca, E Antonio
Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus
title Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus
title_full Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus
title_fullStr Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus
title_full_unstemmed Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus
title_short Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus
title_sort mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850294/
https://www.ncbi.nlm.nih.gov/pubmed/24319635
http://dx.doi.org/10.4161/onci.25620
work_keys_str_mv AT hollontoddc mutationsinglioblastomaoncosuppressivepathwayspavethewayforoncomodulatoryactivityofcytomegalovirus
AT pricerichardl mutationsinglioblastomaoncosuppressivepathwayspavethewayforoncomodulatoryactivityofcytomegalovirus
AT kwonchanghyuk mutationsinglioblastomaoncosuppressivepathwayspavethewayforoncomodulatoryactivityofcytomegalovirus
AT chioccaeantonio mutationsinglioblastomaoncosuppressivepathwayspavethewayforoncomodulatoryactivityofcytomegalovirus