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Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration
Advances in stem cell biotechnology hold great promise in the field of tissue engineering and regenerative medicine. Of interest are marrow mesenchymal stem cells (MSCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). In addition, amniotic fluid stem cells (AFSCs) have attr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royan Institute
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850304/ https://www.ncbi.nlm.nih.gov/pubmed/24520432 |
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author | Baghaban Eslaminejad, Mohamadreza Jahangir, Shahrbanoo |
author_facet | Baghaban Eslaminejad, Mohamadreza Jahangir, Shahrbanoo |
author_sort | Baghaban Eslaminejad, Mohamadreza |
collection | PubMed |
description | Advances in stem cell biotechnology hold great promise in the field of tissue engineering and regenerative medicine. Of interest are marrow mesenchymal stem cells (MSCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). In addition, amniotic fluid stem cells (AFSCs) have attracted attention as a viable choice following the search for an alternative stem cell source. Investigators are interested in these cells because they come from the amniotic fluid that is routinely discarded after birth. There have been multiple investigations conducted worldwide in an attempt to better understand AF-SCs in terms of their potential use in regenerative medicine. In this review we give a brief introduction of amniotic fluid followed by a description of the cells present within this fluid. Their history related to stem cell discovery in the amniotic fluid as well as the main characteristics of AF-SCs are discussed. Finally, we elaborate on the potential for these cells to promote regeneration of various tissue defects, including fetal tissue, the nervous system, heart, lungs, kidneys, bones, and cartilage. |
format | Online Article Text |
id | pubmed-3850304 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Royan Institute |
record_format | MEDLINE/PubMed |
spelling | pubmed-38503042014-02-11 Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration Baghaban Eslaminejad, Mohamadreza Jahangir, Shahrbanoo Int J Fertil Steril Review Article Advances in stem cell biotechnology hold great promise in the field of tissue engineering and regenerative medicine. Of interest are marrow mesenchymal stem cells (MSCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). In addition, amniotic fluid stem cells (AFSCs) have attracted attention as a viable choice following the search for an alternative stem cell source. Investigators are interested in these cells because they come from the amniotic fluid that is routinely discarded after birth. There have been multiple investigations conducted worldwide in an attempt to better understand AF-SCs in terms of their potential use in regenerative medicine. In this review we give a brief introduction of amniotic fluid followed by a description of the cells present within this fluid. Their history related to stem cell discovery in the amniotic fluid as well as the main characteristics of AF-SCs are discussed. Finally, we elaborate on the potential for these cells to promote regeneration of various tissue defects, including fetal tissue, the nervous system, heart, lungs, kidneys, bones, and cartilage. Royan Institute 2012 2012-12-17 /pmc/articles/PMC3850304/ /pubmed/24520432 Text en Any use, distribution, reproduction or abstract of this publication in any medium, with the exception of commercial purposes, is permitted provided the original work is properly cited http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Baghaban Eslaminejad, Mohamadreza Jahangir, Shahrbanoo Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration |
title | Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue
Regeneration |
title_full | Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue
Regeneration |
title_fullStr | Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue
Regeneration |
title_full_unstemmed | Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue
Regeneration |
title_short | Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue
Regeneration |
title_sort | amniotic fluid stem cells and their application in cell-based tissue
regeneration |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850304/ https://www.ncbi.nlm.nih.gov/pubmed/24520432 |
work_keys_str_mv | AT baghabaneslaminejadmohamadreza amnioticfluidstemcellsandtheirapplicationincellbasedtissueregeneration AT jahangirshahrbanoo amnioticfluidstemcellsandtheirapplicationincellbasedtissueregeneration |