Myeloproliferative neoplasms in five multiple sclerosis patients()

The concurrence of myeloproliferative neoplasms (MPNs) and multiple sclerosis (MS) is unusual. We report five patients from a localized geographic area in Denmark with both MS and MPN; all the patients were diagnosed with MPNs in the years 2007–2012. We describe the patients' history and treatm...

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Detalles Bibliográficos
Autores principales: Thorsteinsdottir, Sigrun, Bjerrum, Ole Weis, Hasselbalch, Hans Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850374/
https://www.ncbi.nlm.nih.gov/pubmed/24371783
http://dx.doi.org/10.1016/j.lrr.2013.06.004
Descripción
Sumario:The concurrence of myeloproliferative neoplasms (MPNs) and multiple sclerosis (MS) is unusual. We report five patients from a localized geographic area in Denmark with both MS and MPN; all the patients were diagnosed with MPNs in the years 2007–2012. We describe the patients' history and treatment. A potential link between MS and MPNs has not been previously recognized. This observation calls attention to potential environmental factors and/or previously unrecognized genetic factors predisposing these patients to both MS and MPNs.

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