Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis()

Frequency of additional chromosomal abnormalities in chronic myeloid leukemia (CML) is estimated to be 7% in chronic phase and increases to 40–70% in advanced disease. Progression of CML from chronic phase to accelerated phase or blast crisis is often associated with secondary chromosomal aberration...

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Autores principales: Calderón-Cabrera, C., Montero, I., Morales, R.M., Sánchez, J., Carrillo, E., Caballero-Velázquez, T., Prats, C., Bernal, R., De Blas, J.M., Pérez-Simón, J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850375/
https://www.ncbi.nlm.nih.gov/pubmed/24371788
http://dx.doi.org/10.1016/j.lrr.2013.08.001
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author Calderón-Cabrera, C.
Montero, I.
Morales, R.M.
Sánchez, J.
Carrillo, E.
Caballero-Velázquez, T.
Prats, C.
Bernal, R.
De Blas, J.M.
Pérez-Simón, J.A.
author_facet Calderón-Cabrera, C.
Montero, I.
Morales, R.M.
Sánchez, J.
Carrillo, E.
Caballero-Velázquez, T.
Prats, C.
Bernal, R.
De Blas, J.M.
Pérez-Simón, J.A.
author_sort Calderón-Cabrera, C.
collection PubMed
description Frequency of additional chromosomal abnormalities in chronic myeloid leukemia (CML) is estimated to be 7% in chronic phase and increases to 40–70% in advanced disease. Progression of CML from chronic phase to accelerated phase or blast crisis is often associated with secondary chromosomal aberrations. We report an exceptional case of CML as debut in lymphoblastic blast crisis and a subsequent progression in myeloblastic blast crisis with rare cytogenetic abnormalities.
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spelling pubmed-38503752013-12-26 Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis() Calderón-Cabrera, C. Montero, I. Morales, R.M. Sánchez, J. Carrillo, E. Caballero-Velázquez, T. Prats, C. Bernal, R. De Blas, J.M. Pérez-Simón, J.A. Leuk Res Rep Case Report Frequency of additional chromosomal abnormalities in chronic myeloid leukemia (CML) is estimated to be 7% in chronic phase and increases to 40–70% in advanced disease. Progression of CML from chronic phase to accelerated phase or blast crisis is often associated with secondary chromosomal aberrations. We report an exceptional case of CML as debut in lymphoblastic blast crisis and a subsequent progression in myeloblastic blast crisis with rare cytogenetic abnormalities. Elsevier 2013-09-21 /pmc/articles/PMC3850375/ /pubmed/24371788 http://dx.doi.org/10.1016/j.lrr.2013.08.001 Text en © 2013 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Calderón-Cabrera, C.
Montero, I.
Morales, R.M.
Sánchez, J.
Carrillo, E.
Caballero-Velázquez, T.
Prats, C.
Bernal, R.
De Blas, J.M.
Pérez-Simón, J.A.
Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis()
title Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis()
title_full Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis()
title_fullStr Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis()
title_full_unstemmed Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis()
title_short Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis()
title_sort differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis()
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850375/
https://www.ncbi.nlm.nih.gov/pubmed/24371788
http://dx.doi.org/10.1016/j.lrr.2013.08.001
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