Remarkable Variation in the Informativeness of RFLP Markers Linked to Hemophilia B Locus in Indian Population Groups: Implication in the Strategy for Carrier Detection

Hemophilia B, an X-linked recessive bleeding disorder, is caused by heterogeneous mutations in the factor IX (F9) gene. Hence, carriers of the disease are usually detected by F9 gene linked RFLP analysis. We aimed to test a set of RFLP markers (DdeI, XmnI, MnlI, TaqI & HhaI), used worldwide for...

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Detalles Bibliográficos
Autores principales: Mukherjee, S., Saha, A., Kumar P., Senthil, Chandak, G. R., Majumder, P. P., Ray, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2006
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850563/
https://www.ncbi.nlm.nih.gov/pubmed/17264403
http://dx.doi.org/10.1155/2006/947275

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