Cargando…

Determination of Glutamic Acid Decarboxylase (GAD65) in Pancreatic Islets and Its In Vitro and In Vivo Degradation Kinetics in Serum Using a Highly Sensitive Enzyme Immunoassay

Glutamic acid decarboxylase GAD65 autoantibodies (GADA) are an established marker for autoimmune diabetes. Recently, the autoantigen GAD65 itself was proposed as biomarker of beta-cell loss for prediction of autoimmune diabetes and graft rejection after islet transplantation. Therefore, the GAD65 co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schlosser, Michael, Walschus, Uwe, Klöting, Ingrid, Walther, Reinhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2008
Materias:	Other
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850600/ https://www.ncbi.nlm.nih.gov/pubmed/18334741 http://dx.doi.org/10.1155/2008/961421

Ejemplares similares

Hypercapnic ventilatory response in mice lacking the 65 kDa isoform of Glutamic Acid Decarboxylase (GAD65)
por: Bissonnette, John M, et al.
Publicado: (2004)

Identification of a dominant epitope of glutamic acid decarboxylase (GAD-65) recognized by autoantibodies in stiff-man syndrome
Publicado: (1993)

A novel expression platform for the production of diabetes-associated autoantigen human glutamic acid decarboxylase (hGAD65)
por: Wang, Xiaofeng, et al.
Publicado: (2008)

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes
Publicado: (1996)

Anti-Glutamic Acid Decarboxylase (GAD) 65 Encephalitis Mistaken for Herpes Encephalitis and Hashimoto’s Encephalitis (HE): A Case Report
por: Abu-Abaa, Mohammad, et al.
Publicado: (2023)

Assessment of CD4+ T Cell Responses to Glutamic Acid Decarboxylase 65 Using DQ8 Tetramers Reveals a Pathogenic Role of GAD65 121–140 and GAD65 250–266 in T1D Development
por: Chow, I-Ting, et al.
Publicado: (2014)

Amino acid residues 24-31 but not palmitoylation of cysteines 30 and 45 are required for membrane anchoring of glutamic acid decarboxylase, GAD65
Publicado: (1994)

Two putative glutamate decarboxylases of Streptococcus pneumoniae as possible antigens for the production of anti-GAD65 antibodies leading to type 1 diabetes mellitus
por: García, Ernesto
Publicado: (2023)

Impact of GAD65 and IA2 autoantibodies on islet allograft survival
por: Lemos, Joana R. N., et al.
Publicado: (2023)

CD4(+) T Cells from Glutamic Acid Decarboxylase (GAD)65-specific T Cell Receptor Transgenic Mice Are Not Diabetogenic and Can Delay Diabetes Transfer
por: Tarbell, Kristin V., et al.
Publicado: (2002)

Gender Differences in Associations of Glutamate Decarboxylase 1 Gene (GAD1) Variants with Panic Disorder
por: Weber, Heike, et al.
Publicado: (2012)

An analytical comparison of three immunoassay platforms for subpicomolar detection of protein biomarker GAD65
por: Costa, Olivier R., et al.
Publicado: (2018)

Glutamic acid decarboxylase (anti-GAD) & tissue transglutaminase (anti-TTG) antibodies in patients with thyroid autoimmunity
por: Marwaha, R.K., et al.
Publicado: (2013)

Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish
por: Zhang, Yifan, et al.
Publicado: (2017)

Weak Association Between the Glutamate Decarboxylase 1 Gene (GAD1) and Schizophrenia in Han Chinese Population
por: Zhang, Luwen, et al.
Publicado: (2021)

Pathogenic Roles of Glutamic Acid Decarboxylase 65 Autoantibodies in Cerebellar Ataxias
por: Mitoma, Hiroshi, et al.
Publicado: (2017)

The early detection of type 1 diabetes mellitus and latent autoimmune diabetes in adults (LADA) through rapid test reverse-flow immunochromatography for glutamic acid decarboxylase 65 kDa (GAD(65))
por: Aulanni'am, Aulanni'am, et al.
Publicado: (2021)

A comparative study of extraction techniques for maximum recovery of glutamate decarboxylase (GAD) from Aspergillus oryzae NSK
por: Lee Ying Yeng, Audrey, et al.
Publicado: (2013)

Concomitant Crohn’s Disease and Anti-Glutamic Acid Decarboxylase (GAD)-Associated Autoimmune Encephalitis: A Case Report
por: Akkoyun, Erkam, et al.
Publicado: (2023)

Glutamate decarboxylase 67 contributes to compensatory insulin secretion in aged pancreatic islets
por: Cho, Jung Hoon, et al.
Publicado: (2019)

Epilepsy in patients with insulin-dependent diabetes and relation to glutamic acid decarboxylase 65
por: Mahmoud, Adel A., et al.
Publicado: (2020)

Bypassing Glutamic Acid Decarboxylase 1 (Gad1) Induced Craniofacial Defects with a Photoactivatable Translation Blocker Morpholino
por: O’Connor, Matthew J., et al.
Publicado: (2018)

Expression and Transformation Characteristics of a Novel Glutamic Acid Decarboxylase LcGAD10s and Its Application on Sufu Processing
por: Chen, Zhou, et al.
Publicado: (2023)

Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome
por: Gu Urban, Gucci Jijuan, et al.
Publicado: (2015)

Decline in Titers of Anti-Idiotypic Antibodies Specific to Autoantibodies to GAD65 (GAD65Ab) Precedes Development of GAD65Ab and Type 1 Diabetes
por: Larsson, Helena Elding, et al.
Publicado: (2013)

Danish children born with glutamic acid decarboxylase-65 and islet antigen-2 autoantibodies at birth had an increased risk to develop type 1 diabetes
por: Eising, Stefanie, et al.
Publicado: (2011)

A randomized trial of oral gamma aminobutyric acid (GABA) or the combination of GABA with glutamic acid decarboxylase (GAD) on pancreatic islet endocrine function in children with newly diagnosed type 1 diabetes
por: Martin, Alexandra, et al.
Publicado: (2022)

Calpain Cleavage of Brain Glutamic Acid Decarboxylase 65 Is Pathological and Impairs GABA Neurotransmission
por: Buddhala, Chandana, et al.
Publicado: (2012)

An Analysis of the Cross-Reactivity of Autoantibodies to GAD65 and GAD67 in Diabetes
por: Jayakrishnan, Bindu, et al.
Publicado: (2011)

Spatially localised expression of the glutamate decarboxylase gadB in Escherichia coli O157:H7 microcolonies in hydrogel matrices
por: Saint Martin, Cédric, et al.
Publicado: (2023)

Meningoencephalitis associated with GAD65 autoimmunity
por: Kuang, Zuying, et al.
Publicado: (2023)

GAD65 Antibody-Associated Epilepsy
por: Valinčiūtė, Justina, et al.
Publicado: (2023)

How Much GAD65 Do You Have? High Levels of GAD65 Antibodies in Autoimmune Encephalitis
por: Gaspard, Nicolas
Publicado: (2020)

A Diagnostic Dilemma of Antiglutamic Acid Decarboxylase 65 (Anti-GAD 65) and Mycoplasma Pneumoniae Antibodies in a Girl Presenting with Acute-Onset Obsessive-Compulsive Disorder
por: Freeman, Cecilia G., et al.
Publicado: (2021)

α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody–positive individuals
por: Doliba, Nicolai M., et al.
Publicado: (2022)

Glutamic Acid Decarboxylase (GAD-65) Autoimmunity Associated With Profound Daytime Hypersomnia, Nighttime Insomnia, Mild Autonomic Neuropathy and Axonal Sensori-Motor Polyneuropathy: A Case Report on a New Phenotype
por: Kesserwani, Hassan
Publicado: (2020)

Clinical and Genetic Characteristics of Non-Insulin-Requiring Glutamic Acid Decarboxylase (GAD) Autoantibody-Positive Diabetes: A Nationwide Survey in Japan
por: Yasui, Junichi, et al.
Publicado: (2016)

Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus
por: Pedotti, Rosetta, et al.
Publicado: (2003)

Expression of recombinant glutamic acid decarboxylase in insect larvae and its application in an immunoassay for the diagnosis of autoimmune diabetes mellitus
por: Trabucchi, Aldana, et al.
Publicado: (2019)

Fine Mapping of Glutamate Decarboxylase 65 Epitopes Reveals Dependency on Hydrophobic Amino Acids for Specific Interactions
por: Valdarnini, Niccolò, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m8nsdnruul1mi5d7lv2ug9r255