TGF-β Signaling in Neuronal Stem Cells

Transforming growth factor beta (TGF-β) signaling has diverse and complex roles in various biological phenomena such as cell growth, differentiation, embryogenesis and morphogenesis. ES cells provide an essential model for understanding the role of TGF-β signaling in lineage specification and differ...

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Detalles Bibliográficos
Autores principales: Yun, Chohee, Mendelson, Jonathan, Blake, Tiffany, Mishra, Lopa, Mishra, Bibhuti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2008
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850609/
https://www.ncbi.nlm.nih.gov/pubmed/18525119
http://dx.doi.org/10.1155/2008/747343
Descripción
Sumario:Transforming growth factor beta (TGF-β) signaling has diverse and complex roles in various biological phenomena such as cell growth, differentiation, embryogenesis and morphogenesis. ES cells provide an essential model for understanding the role of TGF-β signaling in lineage specification and differentiation. Recent studies have suggested significant role of TGF-β in stem/progenitor cell biology. Here in this review, we focus on the role of the TGF-β superfamily in neuronal development.

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